Lesson 3 – Aromatase: The Testosterone Thief


References:

  • G, Williams. “Aromatase Up-Regulation, Insulin and Raised Intracellular Oestrogens in Men, Induce Adiposity, Metabolic Syndrome and Prostate Disease, via Aberrant ER-α and GPER Signalling – PubMed.” Molecular and Cellular Endocrinology, vol. 351, no. 2, Apr. 2012
  • Brown, Katherine A., et al. “Obesity and breast cancer: role of estrogens and the molecular mechanisms involved.” European Journal of Cancer 46.5 (2010)
  • CA, Allan, and McLachlan RI. “Androgens and Obesity – PubMed.” Current Opinion in Endocrinology, Diabetes, and Obesity, vol. 17, no. 3, June 2010.
  • S, Chottanapund, et al. “Anti-Aromatase Effect of Resveratrol and Melatonin on Hormonal Positive Breast Cancer Cells Co-Cultured with Breast Adipose Fibroblasts – PubMed.” Toxicology in Vitro : An International Journal Published in Association with BIBRA, vol. 28, no. 7, Oct. 2014.
  • Ye, Li, Fang-Leung Cheung, and Leonard K. Leung. “The Citrus Flavonone Hesperetin Inhibits Growth of Aromatase‑Expressing MCF‑7 Tumor in Ovariectomized Athymic Mice.” The Journal of Nutritional Biochemistry 23.10 (2012)
  • Wang, Yiyu, et al. “Citrus Polymethoxyflavones Degrade Estrogen Receptor-Alpha (ERα) and Combine with Tamoxifen for the Treatment of Estrogen Receptor-Positive Breast Cancer – PMC.” Heliyon, vol. 10, no. 12.
  • Yaribeygi, Habib, et al. “Molecular Mechanisms Linking Stress and Insulin Resistance.” EXCLI Journal, vol. 21, Jan. 2022.
  • Rhyu, Jane, and Run Yu. “Newly Discovered Endocrine Functions of the Liver.” World Journal of Hepatology, vol. 13, no. 11, Nov. 2021.
  • Michnovicz, J. J., and H. L. Bradlow. “Induction of Estradiol Metabolism by Dietary Indole-3-Carbinol in Humans.” Journal of the National Cancer Institute, vol. 82, no. 11, June 1990/ 
  • Michnovicz, J. J., et al. “Changes in Levels of Urinary Estrogen Metabolites after Oral Indole-3-Carbinol Treatment in Humans.” Journal of the National Cancer Institute, vol. 89, no. 10, May 1997.